Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
"Migration should be an option, a choice. But for 200 million people, it's a necessity," he told the Thomson Reuters Foundation in a phone interview.
SAN ANTONIO DEL TACHIRA Venezuela (AP) — More than 100000 Venezuelans some of whom drove through the night in caravans crossed into Colombia over the weekend to hunt for food and medicine that are in short supply at home.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Global emissions of greenhouse gases jumped 2.3 percent in 2013 to record levels, scientists reported Sunday, in the latest indication that the world remains far off track in its efforts to control global warming.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
A mother has written a letter in defence of her 14-year-old son who is facing a lawsuit over video game cheats in the US.
When I am creating a light novel, Iam creating it mostly alone. When I am working on anime there is a director andthe staff with a point of view on my works. There usually are several revisionsregarding the storyboard. What is interesting is what will come back. It's avery interesting part of the work.
Trends and targets in antiviral phototherapy
More than 430,000 students from 1,767 universities in 31 provinces, municipalities and autonomous regions across China were surveyed. Of the respondents, 89.2% had considered starting a business, with 18.2% reporting firm intentions to do so.
The end of November is here. As I wrote Monday, recent history suggests nine teams have pretty much already been knocked out of playoff contention. Yet, none of them are straight-up tanking.
Stanford’s alumni have the highest salary on average at $195,000 but overall the top 15 MBA programmes are closely matched in terms of income, career progress and satisfaction. All but one have average alumni salaries greater than $150,000, with a pay increase of about 100 per cent compared with their pre-MBA income.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
China's online game revenue in 2008 was CNY20.8 billion, accounting for about 27% global share, ahead of South Korea at 21% and slightly behind the U.S. at 29%, according to an earlier report by Shanghai-based market research firm iResearch. The firm also predicted that China is likely to surpass the U.S. to become the world's largest by the end of 2009.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
15. 有趣的巧合。环球影业是题材最具多样性的制片公司之一，它发行了《生活残骸》，也发行了《冲出康普顿》，还有《泰迪熊2》(Ted 2)。环球影业的女导演也是最多的，12月初，它占据了今年24%的市场份额。
May its blessings lead into a wonderful year for you and all whom you hold dear.祝福你及你所爱的人新的一年中万事如意。
ACE2 as a potential therapeutic target for pandemic COVID-19
With the release of his book Conscious Capitalism, Whole Foods (WFM, Fortune 500) CEO John Mackey got business leaders thinking about a compelling idea: Companies work best when they create value for all their stakeholders -- not just investors. According to Mackey, key stakeholders include customers, employees, suppliers, society, and the environment. Highlighting companies like Costco, Southwest Airlines (LUV,Fortune 500), and Google (GOOG, Fortune 500), Mackey demonstrates that thinking about more than just the bottom line builds stronger and more efficient businesses.
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
n. 史诗，叙事诗 adj. 史诗的，叙事诗的，宏大的，
It is the thirdhighest overall behind the two Indian management academies at Ahmedabad and Bangalore, with respective salaries of $109,000 and $106,000.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
After Zhou contaminated the water, one of Zhou's classmates surnamed Tang noticed that the water coming out of the dispenser was milky and had a pungent scent.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Also featured in the 2013 top 10 were Singapore, Zurich, Paris, the Venezuelan capital of Caracas and Geneva.
One side of the capsized Eastern Star was rolled above water at 7:30 am Friday, as rescuers worked through the night to right the upturned ship in the Yangtze River. The side that has emerged shows "Eastern Star" in Chinese character on the hull.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
More than 40 percent of consumer goods exported to China last year through e-commerce platforms fell short of standards, China's top quality watchdog said.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
It's hard enough for NBA defenders to stop Rose, so just imagine how ridiculously hard that must have been back in high school with Rose being nearly the same size that he is now.
Antiviral drug discovery: broad-spectrum drugs from nature
When she consults managers, Kay says many of them suspect something is fishy when their employees stop talking to them as often, whether it's to give an update, ask for an opinion or just say hello. As Kay puts it: "You're not doing the things you normally would have to keep the relationship going."
Influenza neuraminidase: A druggable target for natural products
It is the first time that EMBA-Global, the joint programme delivered by London Business School and Columbia Business School, has dropped out of the top five.
The dollar value of China’s exports fell markedly more than expected last month and import growth more than halved, while revisions to November data erased what had appeared to be a long-hoped-for return to growth for outbound shipments.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The runner-up was Lucy Kay, with Bars and Melody in third place.
贝恩公司(Bain & Company)也正处于变革之中，去年11月该公司宣布曼尼马塞达(Manny Maceda)将于2018年3月成为其全球领导人，从鲍勃博切克(Bob Bechek)手中接管这家总部位于波士顿的咨询机构；马塞达将是该公司首位亚洲血统的掌门人。专家们表示，马塞达可能推动该公司开拓新的专长领域，并摆脱业务多而不精的名声。
The role of biosensors in the detection of emerging infectious diseases
But many others cities that have featured prominently in recent months remained relatively undaunted by the new popularity of purchasing curbs, as prices remained substantially elevated from a year earlier.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
This year's new college grads entering the workforce are being offered an average monthly salary of 4,014 yuan ($582), and about one-third of them chose to work in first-tier cities, according to survey results released by zhaopin.com, a Chinese online recruitment service provider.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Best chance: If there are nine or 10 best picture nominees, it could grab a spot. Jordan Peele's screenplay looks certain to be recognized.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
The values of the citizenry are a democracy’s most important asset.
Inhibition of SARS coronavirus helicase by bismuth complexes
Banks, asset managers and insurance companies have flocked from mainland China to acquire prime Hong Kong office buildings, prompting the territory’s government to announce it will release more land for commercial redevelopment in the oversubscribed heart of the city.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Add your scores for 10 to 14 to find out how you score on the Social Inhibition scale.
《倒霉蛋：罗伯特·博斯特的生与死》(Jinx: The Life and Deaths of Robert Durst)，HBO，2月8日播出。《追捕弗雷德曼家族》(Capturing the Friedmans)的导演安德鲁·杰瑞克奇(Andrew Jarecki)执导了这部六集系列纪录片，在片中与博斯特先生通力合作。博斯特出身纽约房地产世家，与数起谋杀事件有关，他的第一任妻子失踪之谜至今未曾解开。
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Uruguay represents a more curious case, in that its players are footballing aristocracy disguised as minnows. Like Belgium, it is a relatively young nation, yet on the field of play the Uruguayans are old hands. They have won the World Cup twice, first at the inaugural event in 1930, and then in 1950, when Brazil hosted the tournament. The latter occasion, when Brazil succumbed in front of a world-record 200,000 fans or more, is referred to there as the "Maracanazo", a national tragedy still felt today.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
The three bubbles: The Asian Bubble in the early '90s, Dot-com Bubble of the late '90s and what Juckes calls the Great Big Credit Bubble that triggered the 2008 Wall Street meltdown.
Song “Happiness” (Mao A’Min)
"Let me point to the performance of China, in coming in at number 25 in the rankings, is now joining the upper income group of countries that have traditionally dominated the top slots in the global innovation index," the WIPO director-general, Francis Gurry, told a news conference.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
With the compliments of the season.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
1) I make contact easily when I meet people 0 1 2 3 4
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
In a bid to raise awareness of one of the world's most endangered species and the Chengdu Panda Base in China, the 108 performers were hard to miss as they entertained Londoners and children during school visits with conservationist and base ambassador Nigel Marven.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Many economists doubt the European Central Bank will increase the size of its 1.46tn asset-purchase programme in 2016 despite assurances by ECB chief Mario Draghi that additional monetary stimulus is still on the table.
Having said this, don't make a pest of yourself. Nobody wants to hear you ask a question every 10 minutes. If you're completely lost, make an appointment to see your teacher after class.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Hannah Kuchler is San Francisco correspondent
A Florida teen is causing strangers to freeze and stare because of her uncanny likeness to Queen Elsa from the Disney movie Frozen.
Warm greetings and best wishes for the New Year!致以热烈的祝贺和良好的祝福,新年快乐。
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
'Nebraska' gets to the heart of Bruce Dern's prickly old geezer, Woody Grant, by way of a road trip across Montana and Nebraska, shot in radiant black-and-white. (Here again one of the movie's stars is its cinematographer, Phedon Papamichael.) Alexander Payne directed, flawlessly, from Bob Nelson's stellar script, which is all about thwarted love, and reconciliation, between Woody and his son Will; he's played with painfully quiet eloquence by Will Forte. Here's the American heartland as it's seldom portrayed on screen, with humor and almost palpable fondness.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Most common passwords of 2013:
A record 27,817 civil service jobs are being offered this year by central government departments and subsidiaries.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Although Chinese domestic suppliers have expanded their market share to 32.7% in 2016, the trend was reversed in 2017, as their share shrank to 26.8%, said Qu Daokui, president of China Robot Industry Alliance.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Obama watched the returns on television at his Chicago home. Senior campaign strategist David Axelrod said via email that he was feeling "great."
In 2013, the yen fell 21% against the U.S. dollar, helping it to attract 10 million overseas tourists--including, despite Sino-Japanese border disputes in the East China Sea, many wealthy travelers from China.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Wang Ki-young, a director at South Korea’s culture ministry, said on Friday that Chinese authorities had ordered tourism agencies in Beijing to halt tours to South Korea from mid-March. Mr Wang said the move would be expanded to other provinces.
5. Will China's migrant workers get permanent urban residence in 2010?
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
In the wake of the Fitbit and Google’s GOOG 0.26% Glass, a flurry of companies has flooded the market with iterations of sensor-laden armbands, apparel, and eyewear. It’s a buzzy category, but early adopters seem to be waiting for a moment when they are no longerthat guy. (You know. The “Glasshole.”)
Industrial production rose 6.1 per cent year on year in October, according to China’s National Bureau of Statistics, unchanged from September’s level and just below a median forecast from economists of 6.2 per cent.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
We will endeavor to transform and upgrade traditional industries.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
“Why did this happen to my daughter?” she said. “There’s been so many deaths because of the guns. I don’t know how many people have to die.”
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The only thing worse than being bad is being bad without a vision. Johnson never lacked vision as a player and he's off to a good start as an executive.
With most of our favorite shows on or approaching the dreaded holiday hiatus, it's time to reflect on the women that made the fall 2011 TV season so great.
A facile assay for rapid detection of COVID-19 antibodies
The area is close to the city centre and the demolition contractors had to make sure that when they brought down the buildings they did not damage a light rail viaduct nearby or a shopping mall and electricity sub-station.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
The 60-episode TV drama was adapted from a novel Legend of Princess Pearl published in 2007. It focuses on the protagonist Shen Zhenzhu’s romance with her husband and their efforts to protect the country.
Whether or not any sort of BlackBerry-Samsung deal actually happens, the development highlights next wave of innovation (and litigation) in mobile technology: one centered on access control methods and containing corporate breachesin an increasingly mobile world.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Hayley Williams remains a powerful up-front presence, a belter who can croon as convincingly as she can yelp. Her vocal bravado almost makes you forget that After Laughter is an up-close chronicle of her weariness with the world.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
It's lightweight and rolls up easily for travel.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Sales of previously owned homes have slipped every month since July, according to the National Association of Realtors. That coincides with the surge in borrowing costs across the economy as a result of the Fed's signals about its bond-buying program.
Anti-HIV drug repurposing against SARS-CoV-2
7The United States
Length-scale dependence of protein hydration-shell density
“能够有这些天赋异禀的艺术家为电影的音乐进行神助攻，我们非常能高兴。”这场秀的制作人Michael De Luca 和Jennifer Todd周五发表申明时如是说。“能邀请到他们登上第90届奥斯卡也是一种荣幸。”
Interestingly, a survey found Beijing was thought to be the most congested city in China, among 31.8 percent of respondents, followed by Zhengzhou at 8.8 percent.
“In the drama, romance is the protagonist’s only pursuit. It seems that the meaning of her life is to have a romantic relationship with a Prince Charming. No, not only one, but three or four,” Douban user Jiuyuehuashang said.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
8. Ford Motor
An Australian woman whose cats ate each other after she abandoned them in her home has been convicted of animal cruelty.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
You can make eye contact with the professor. Don't underestimate the power of this. If your teacher knows you're really listening and that you care about what you're learning, he or she will be extra willing to help you. Besides, it'll feel like you've got your own private teacher.
About this collection
One of the things that makes Guardians such a great superhero franchise is its sense of humor—which is full of self-deprecation and sarcasm. It's not like you're going to watch this movie and laugh your way through it, but you'll at least have some moments of "ha ha, Groot," and "lolololol Chris Pratt."